She has also appeared on Jerry Seinfeld’s popular Netflix series, Comedians in Cars Getting Coffee and hosts her popular weekly podcast, Madigan's Pubcast which currently has over 5 million downloads on all streaming outlets.

Her most recent special Hunting Bigfoot, an Amazon Original, is her sixth hour long stand-up special released on the heels of her critically acclaimed and third Netflix special, Bothering Jesus. The brand-new special, recorded at The Paramount Theatre in Denver, CO explores topics including Madigan’s aging parents, interactions with millennials and hunting bigfoot.

Kathleen’s album of the Bothering Jesus special was the highest selling comedy album and most played comedy album on streaming services since 2014.

Madigan has performed internationally at festivals in theaters in Ireland, England, Hong Kong, Australia and has filmed seven Montreal Gala Shows at the Just For Laugh’s Comedy Festival for CBC TV.

Chicago Tribune wrote, “She has all but perfected the art of crafting and delivering a perfect joke. That singular dedication to the craft shows in both the evolution of her material over the years and way she can make a complicated joke with a hidden nub of wisdom seem both effortless and offhand.”

“There's nobody better than Maddy. She’s smart and just crushes it every time. She's not just one of the best 'female' comics, she's one of the best comics, period,” says comedian Ron White.

She's won the American Comedy Award for "Best Female Comedian" and the Phyllis Diller award for "Best Female Comedian." She has written and produced for Lewis Black's Root of All Evil on Comedy Central and done multiple USO tours in Iraq and Afghanistan.