Serena has a unique ability to cross genres – from pop, to folk and roots, to Christmas and children's music. Her diverse catalogue has earned her several accolades, including Canada's Walk of Fame Allan Slaight Music Impact Honour, the Margaret Trudeau Mental Health Advocacy Award, a Canada Folk Music Award and Canadian Screen Award for Achievement in Music–Original Song.

Serena is a mental-wellness advocate who has shared her own story of depression and neuro-divergency publicly, and speaks across the country to thousands of people each year. Her song "What I Wouldn't Do" was reimagined for Kids Help Phone's Feel Out Loud 2023 campaign — the largest mental health campaign in Canadian history. Serena also works with emerging musicians and industry professionals through her ArtHaus Community non profit, helping them develop creative, entrepreneurial and wellness skills needed to thrive in today's music and media landscape.